PCP effects can be very unpredictable. Central Nervous System effects can include euphoria, loss of inhibitions, anxiety, disorientation, restlessness, drowsiness, or disorganized thinking. There can also be distorted time, space, and body sensations, feelings of weightlessness, paranoia, and the feeling of being disassociated with the environment. The user can experience audial and visual hallucinations as with LSD. In the body, PCP raises the heart rate and blood pressure. It can also cause excess salivation, sweating, numbness, staggering, slurred speech, fever, and muscle rigidity.
In toxic doses, the user can become hostile and violent, acting in a bizarre or psychotic manner. They may attempt to assault other people, or to harm themselves through self-mutilation or suicide. The person may experience amnesia and become catatonic. In high doses, there may be coma, convusions, and death. Persons who’ve received toxic doses must often be restrained and receive tranquilizers to calm them down.
Law enforcement authorities say the drug can make people hostile and give them extra physical strength, and the same has been experienced by medical personnel dealing with overdose emergencies. Researchers, however, have generally not observed such results from PCP (although one of the very first studies in the 1950s noted violent reactions from about 5% of surgery patients who received the drug as an anesthetic).
Military research found that PCP hostility did not occur unless persons were under stress, and not all stressed individuals reacted that way. The military study also found that psychotic episodes did not occur with normal persons; someone had to be prone to psychosis in order for such behavior to occur while using the drug (a finding supported by other studies as well)
Long term effects
PCP is addicting; that is, its repeated use often leads to psychological dependence, craving, and compulsive PCP-seeking behavior.
Recent research suggests that repeated or prolonged use of PCP can cause withdrawal syndrome when drug use is stopped. Symptoms such as memory loss, difficulties with speech and thinking, weight loss and depression may persist for as long as a year after a chronic user stops taking PCP.
A study of 200 recreational users found differences in effects reported by persons who took a little of the drug once a month and by persons who took a lot every day for years. Heavy users felt more pepped-up, violent, and suicidal. Regular users of PCP are known for self-destruction; one study found that 24% of regular users had tried to commit suicide, and 36% had overdosed on other drugs. A study of PCP users who were treated at a charity hospital found no behavioral difference between black or white males, but black females acted much stranger and more aggressively than white females. The meaning of that finding is unclear—it could be racial, could be cultural, could be a statistical oddity that would disappear after more research